Your healthcare provider will determine the right dosage and form for you based on your specific needs and health condition
In contrast, stimulant-based medications like phentermine cause increased energy and jitteriness rather than fatigue but come with different side effects

Pharmaceutical semaglutide (Wegovy/Ozempic): Retail price: $1,000-1,500 per month With insurance: $25-$300 per month (if covered) Annual cost: $12,000-18,000 without insurance Insurance coverage: Inconsistent, many plans don't cover weight loss Pharmaceutical tirzepatide (Zepbound/Mounjaro): Retail price: $1,000-1,500 per month With insurance: $25-$300 per month (if covered) Annual cost: $12,000-18,000 without insurance Insurance coverage: Even less consistent than semaglutide Research peptide semaglutide: Cost: $150-250 per month at therapeutic doses No insurance involvement Annual cost: $1,800-3,000 Must reconstitute yourself from powder Research peptide tirzepatide: Cost: $200-300 per month at therapeutic doses No insurance involvement Annual cost: $2,400-3,600 Must reconstitute yourself from powder Research peptides are 80-90% cheaper than pharmaceutical versions

For the approved drugs, the following table summarizes the data from clinical trials on weight loss and how long it may take to get there
In addition, we allowed a rate of withdrawal or loss to follow-up of up to 10%